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KMID : 0380319750150000313
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Journal of Korean Research Institute for Better Living
1975 Volume.15 No. 0 p.313 ~ p.330
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Study on δ-ALA in Urine of the Workers
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Abstract
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δamino levulinic acid is a intermediate of the biosynthesis of heme, and the absorption of lead inhibites δALA dehydratase and accumulates δALA in vivo. The δALA is excreted in urine.
Singerman A. and Djuric D. proved that urinary δALA is induced by the absorption of lead. And so lead poisoning of a specimen of occupational exposure can be diagnosed early by measuring the excretion of urinary ALA content.
The samples of this study were randomly selected from 324 specimen in normal specimen, dwellers around bus stopareas, traffic policemen, profe´ssional drivers, printing workers, type pickers, type foundrers, paint workers, plastic container workers, and dry cell(battery) workers, and experimented urinary ALA content by wada｀s method.
The results of the study are as follows:
(1)Urinary ALA contents of drivers, type foundrers, paint workers and dry cell workers group were remarkably higher than other group.
(2)The specimen, whose concentration of ALA in urine were higher than 4.0㎎/l were 40 among 324(12.3%) and whose concentration of ALA in urine were higher than 4.5㎎/l were 28 among 324(8.6%).
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